Young hearts age fast in new hosts
new research finds transplanted hearts in mice and humans adopt biological age of recipient quickly. this challenges idea of rejuvenation through young organ transplants.
researchers at brigham and women's hospital transplanted young and old hearts into mice, finding that transplanted hearts adopted the biological age of the recipient within months. human heart transplant data supported these findings. the study used 'aging clocks' to assess biological age. results suggest that the environment of the transplanted organ dictates its biological behavior. this challenges the idea that young organs can rejuvenate older individuals.