Google DeepMind's AlphaGenome 2 predicts genetic variant effects on specific cells

google deepmind unveiled alphagenome 2, a new ai model designed to predict how genetic mutations affect different cells. the model was trained on over 100 million individual cell profiles across 68 tissues, giving it a more detailed view than its predecessor, alphagenome. alphagenome 2 identifies nearly twice as many variants that can change gene expression in cells than its previous state-of-the-art model. this specificity is crucial for understanding how genetic variants affect specific cell types and could lead to new treatments. researchers can now drill down on genetic variants identified in large populations to see their effects on a cellular level and potentially connect those effects to disease.